This book deals with research and findings related to the diseases and pests that affect silkworms. It covers a wide range of topics, including the identification and characterization of a novel variant of the Bombyx mori latent virus that infects Helicoverpa armigera and Trichoplusia ni. Another topic explores the host response to virus infection in silkworms, focusing on the impact of Bidensovirus infection on Bombyx mori. The book also investigates a protein asteroid with a PIN domain in Bombyx mori that is involved in anti-BmNPV (Bombyx mori nuclear polyhedrosis virus) infection. Readers of this book will gain insights into the advances made in the ongoing struggle between silkworms and baculoviruses, as well as the characterization of Klebsiella granulomatis, a pathogen affecting silkworms. Furthermore, the book explores methods of controlling bacterial and fungal diseases in mulberry silkworms through the use of plant extracts. It also covers the rapid detection of infectious Flacherie virus in silkworms and the effects of feeding silkworms with different mulberry genotypes on their development and health, as well as the quality of raw silk.The book is specifically targeted toward those interested in diseases and pests affecting silkworms, providing valuable information on viral and bacterial infections, host responses, and methods for disease control.