Biophysics is a captivating field of scientific inquiry that merges the principles of physics with the study of biological processes. By applying the analytical tools and mathematical laws of physics to living organisms and systems, researchers in biophysics have made profound contributions to various domains, ranging from medicine to environmental sustainability. Biophysics has played a crucial role in the prevention and treatment of diseases. By harnessing biophysical techniques, scientists have developed vaccines that have eradicated or significantly reduced the prevalence of numerous infectious diseases. Moreover, biophysics has facilitated the creation of powerful imaging modalities like Magnetic Resonance Imaging (MRI) and Computerized Axial Tomography (CAT) scans, enabling healthcare professionals to accurately diagnose diseases and guide appropriate treatments. The interdisciplinary nature of biophysics is evident in the book “Biophysics,” which integrates concepts and methods from diverse fields such as physics, biology, biochemistry, colloid chemistry, and physiology. This comprehensive text sheds light on the current state of knowledge concerning biophysical principles governing RNA folding. Notably, it explores the folding of various types of RNAs, including ribosomal RNAs, viral RNAs, and self-splicing introns. By investigating these fundamental processes, researchers gain insights into the intricate mechanisms underlying gene expression and regulation, which have far-reaching implications for both basic science and therapeutic interventions.