Contents? Enzyme Kinetics, Bio-Catalysts, Effectiveness of Enzymes, Proteases, Inhibition of Proteolytic Enzymes, Specific Enzymes, Bio-synthesis of Peptides, Survey and Summary, Evolution of Restriction Endonucleases, Structural Variation of Restriction Endonucleases, EcoRV Endonuclease, Tetrameric Restriction Enzymes, IIE Restriction Endonucleases.